Here was my carefully crafted keyboard concept back from 2010:



I think its function over form, at its max. Keeping the important keys, and hiding the rest as Secondary ones (Activated via Ctrl), and do away with the rest. A small light indicates when Ctrl or the Shift (Caps Lock) is active. The circle at the right is actually a Trackball (think Blackberry) which helps control the cursor with awesome tactile feedback.

All in all, keep everything big, bland, easy to see and type away!