A few hints come to my mind:

- MyMoves by Topi Santakivi lets you launch predefined applications by using gestures

- N9QTweak option to change the icons grid (from default 4 columns to let's say 3 larger ones)

- N9QTweak option to boost the sound volume from default 66% to 100%

- Easy Answer - "When you receive a call, just raise the phone to your ear and it will be answered automatically. When you're done, simply shake the phone to end the call."