Why not? Can't be a big deal imho. Open Pandora or IndieGo! Console can both boot from sd card; they are based on Linux operating systems, Super Zaxxon/IndieGo! OS respectively. The predecessor to the Open Pandora (600 MHz + 1 Ghz variants), the upcoming Dragonbox Pyra by Evil Dragon/Michael Mrozek, will be able to boot from one of the two sdxc card slots, too. As long as you can specify a device type like usb stick, sd card, external hd or NAS drive to boot from and you can secify the boot device order it should be possible, no?