With the following

mount -t binfmt_misc none /proc/sys/fs/binfmt_misc
echo ':i386:M::\x7fELF\x01\x00\x00\x00\x00\x00\x00\x00\ x00\x00\x00\x00\x02\x00\x03:\xff\xff\xff\xff\xff\x fe\xfe\xff\xff\xff\xff\xff\xff\xff\xff\xff\xfb\xff \xff:/home/user/qemu-i386:' >/proc/sys/fs/binfmt_misc/register
echo LD_LIBRARY_PATH=/opt/root/x
~/wine/usr/lib/wine $ file /lib/ld-l*
~/wine/usr/lib/wine $ file -L /lib/ld-l*
/lib/ld-linux.so.2: ELF 32-bit LSB shared object, Intel 80386, version 1 (SYSV), stripped
/lib/ld-linux.so.3: ELF 32-bit LSB shared object, ARM, version 1 (SYSV), stripped
~/wine/usr/lib/wine $

I can simply run arm or x86 linux binaries with reasonable success. fork/clone don't work so wine can't run stuff but will execute:

~/wine/usr/lib/wine $ /usr/bin/file /usr/bin/file
/usr/bin/file: ELF 32-bit LSB executable, ARM, version 1 (SYSV), for GNU/Linux 2.4.17, dynamically linked (uses shared libs), stripped
~/wine/usr/lib/wine $ file ../../bin/wine
../../bin/wine: ELF 32-bit LSB executable, Intel 80386, version 1 (SYSV), for GNU/Linux 2.6.18, dynamically linked (uses shared libs), stripped
~/wine/usr/lib/wine $ wine
qemu: Unsupported syscall: 240
Usage: wine PROGRAM [ARGUMENTS...] Run the specified program
wine --help Display this help and exit
wine --version Output version information and exit
~/wine/usr/lib/wine $ wine --version
qemu: Unsupported syscall: 240
wine-1.1.29