Just for the record:
I tried the original Simcity in Dosbox and in principle it runs. The problem is that you can't scroll in a reasonable way because on the touch screen every cursor movement starts with a click (when touching the screen). This means that whatever tool you have selected in Simcity (bulldoze, build road, etc.) will be executed along the path of your mouse cursor while scrolling.
Since Simcity neither has a "none" tool nor allows scrolling via keyboard it's practically unplayable.